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. 2019 Aug 15;11(8):4667–4682.

Figure 7.

Figure 7

Effect of GEC exosomes treated with low glucose and high glucose on mesangial cells (GMC). (A) Endocytosis analysis of GMCs into GEC exosomes with different glucose treatments. GEC exosomes were labeled with PKH67. Scale bar = (B) Cell proliferation analysis of GMCs treated with different GEC exosome. (C) Expression of circRNF169 and circSTRN3 in GMCs treated with different GEC exosomes. (D) Immunofluorescence analysis of epithelial-mesenchymal transition (EMT) of GMCs treated with different GEC exosomes. (E) ELISA examination of EMT of GMCs treated with different GEC exosomes. *P < 0.05; ***P < 0.001; ****P < 0.0001. Untreated: GMC without treatment. HG-GEC-EXO: exosomes from GMCs treated with high glucose. NG-GEC-EXO: exosomes from GMCs treated with low glucose.