Table 4.

Correlation of STAT family members with smoking history of NSCLC patients

Gene	Smoking history	Low (cases)	High (cases)	HR (95% CI)	p-value
STAT1	Never smoked	103	102	0.73 (0.41-1.28)	0.27
	Smoked	410	410	0.92 (0.75-1.13)	0.41
STAT2	Never smoked	103	102	1.88 (1.06-3.34)	0.027*
	Smoked	410	410	1.27 (1.03-1.56)	0.024*
STAT3	Never smoked	102	103	2.17 (1.21-3.91)	0.0079**
	Smoked	410	410	1.08 (0.88-1.33)	0.48
STAT5A	Never smoked	102	103	1.12 (0.64-1.96)	0.68
	Smoked	410	410	0.89 (0.73-1.1)	0.28
STAT5B	Never smoked	102	103	0.33 (0.18-0.6)	0.00013**
	Smoked	410	410	0.81 (0.66-1)	0.044*
STAT6	Never smoked	102	103	0.87 (0.5-1.51)	0.61
	Smoked	410	410	0.77 (0.63-0.95)	0.013*

Low/High (cases): low/high expression of the corresponding gene (patient number).

^* P < 0.05;

^** P < 0.01.