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. 2019 Aug 15;11(8):4935–4945.

Figure 3.

Figure 3

Inhibiting circ_0039569 suppressed RCC cell proliferation and metastasis. A. Circ_0039569 expression in RCC4 and 786-O cells. RCC4 and 786-O cells were transfected with circ_0039569 shRNA and circ_0039569 levels were analyzed by qRT-PCR. B, C. Down-regulation of circ_0039569 reduced RCC cell proliferation. RCC4 and 786-O cells were transfected with circ_0039569 shRNA and survival ability was analyzed by CCK8 assay. D. Down-regulation of circ_0039569 reduced RCC cell colony numbers. RCC4 and 786-O cells were transfected with circ_0039569 shRNA and survival ability was analyzed by colony formation assay. E. Down-regulation of circ_0039569 reduced migrated RCC cell numbers. RCC4 and 786-O cells were transfected with circ_0039569 shRNA and migration ability was analyzed by wound healing assay. F. Down-regulation of circ_0039569 reduced invaded RCC cell numbers. RCC4 and 786-O cells were transfected with circ_0039569 shRNA and invasion ability was analyzed by transwell chambers with matrigel treatment. Data were expressed as mean ± SD. **P < represents statistical difference.