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. 2019 Aug 15;11(8):4992–5007.

Figure 3.

Figure 3

4-OH E2 suppressed tumor growth in nude mice. The MCF10A-H cells MCF10A-E cells and MCF10A cells were subcutaneously orthotopically injected into mammary two sides of fat pads of BALB/C female nude mice. (A, a) group I MCF10A-H cells and MCF10A cells were injected into two sides of fat pads of 5 mice. 4 mice have MCF10A-H cells tumor on one side. MCF10A cells could not form tumor. (b) group II MCF10A-H cells and MCF10A-E cells were injected into two sides of fat pads of 5 mice. All mice have MCF10A-H cells tumor on one side, and MCF10A-E cells formed smaller tumor volume in 3 mice on the other side. (B) Photographs of tumors from mice. (a) group I, (b) group II. (C) Relative tumor volume of mice. (a) group I, (b) group II.