Table 1.

Estrogen metabolites of premenopausal patients with breast cancer and normal controls

	Control	Breast cancer	P	OR (95% CI)*	P *
Estrone (E1)	3.09 ± 2.18	3.94 ± 3.41	0.23	1.47 (0.84-2.57)	0.18
Estradiol (E2)	1.24 ± 0.81	1.49 ± 0.94	0.23	1.33 (0.83-2.15)	0.24
Estriol (E3)	1.75 ± 1.14	1.55 ± 0.86	0.39	0.8 (0.5-1.26)	0.34
2-OH-E1	0.89 ± 0.68	1.54 ± 1.08	0.01	2.31 (1.27-4.2)	0.01
2-OH-E2	0.25 ± 0.22	0.25 ± 0.15	0.99	1.04 (0.66-1.63)	0.88
2-Methoxy-E1	0.29 ± 0.19	0.73 ± 0.53	<0.01	6.97 (2.26-21.52)	<0.01
2-Methoxy-E2	0.04 ± 0.03	0.07 ± 0.05	<0.01	3.29 (1.66-6.52)	<0.01
4-OH-E1	0.18 ± 0.13	0.59 ± 0.41	<0.01	17.88 (4.05-78.9)	<0.01
4-OH-E2	0.09 ± 0.04	0.15 ± 0.09	<0.01	3.36 (1.6-7.07)	<0.01
4-Methoxy-E1	0.03 ± 0.02	0.05 ± 0.04	0.01	3.06 (1.35-6.95)	0.01
4-Methoxy-E2	0.02 ± 0.02	0.03 ± 0.02	0.22	1.39 (0.84-2.28)	0.2
16α-OH-E1	0.96 ± 0.58	0.87 ± 0.55	0.51	0.89 (0.56-1.4)	0.61

EMs are the estimated standardized regression coefficients.

^* P and OR (95% CI) were adjusted by age and BMI.