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. 2019 Aug 15;11(8):4992–5007.

Table 2.

Estrogen metabolite ratios of patients with breast cancer and normal controls

Control Breast cancer P OR (95% CI)* P *
2-OH-E:E 0.27 ± 0.12 0.35 ± 0.16 0.01 1.494 (0.936-2.385) 0.092
4-OH-E:E 0.08 ± 0.05 0.15 ± 0.06 <0.001 6.43 (2.1-19.63) <0.001
16α-OH-E1:E1 0.36 ± 0.18 0.25 ± 0.13 0.01 0.453 (0.27-0.759) 0.003
2-OH-E1:16α-OH-E1 1.08 ± 0.81 1.97 ± 1.28 <0.001 2.81 (1.45-5.45) 0.003
2-OH-E:4-OH-E 4.26 ± 2.4 2.45 ± 0.85 <0.001 0.17 (0.06-0.49) <0.001
*

P and OR (95% CI) were adjusted by age and BMI.