Table 1.
Prevalence of antibiotic resistance in blood-isolated Enterococcus spp.
| Antibiotic | Enterococcus faecalis | Enterococcus faecium | Enterococcus spp. | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Pooled prevalence (%) (95% CI) | n/N | N of studies | Pooled prevalence (%) (95% CI) | n/N | N of studies | Pooled prevalence (%) (95% CI) |
n/N | N of studies | |
| Vancomycin | 1.6 (1.4–2.5) | 336/14,741 | 88 | 10 (8–13) | 1762/12,695 | 108 | 6.6 (5.7–7.7) | 3029/34,708 | 245 |
| Gentamicin | 36.5 (33–40) | 7167/20,163 | 89 | 46.5 (39–45) | 2019/4196 | 53 | 37.5 (35–40) | 11,284/29,958 | 181 |
| Ampicillin | 4 (2.3–7) | 921/11,047 | 48 | 78 (73–82.5) | 2979/3747 | 45 | 43.5 (39.3–47.8) | 5678/20,870 | 133 |
| Teicoplanin | 2 (1.2–3) | 215/7031 | 41 | 14.5 (9.5–22) | 488/2246 | 36 | 6 (5–6.5) | 1285/14,876 | 110 |
| Linezolid | 0.6 (0.3–1) | 52/8762 | 34 | 1.7 (1–2.8) | 34/3293 | 34 | 0.9 (0.7–1.3) | 104/17,947 | 100 |
| Ciprofloxacin | 43.5 (36–51) | 2855/6840 | 40 | 75 (69–80) | 1944/2513 | 32 | 57.5 (53–61.7) | 6530/12,666 | 99 |
| Streptomycin | 35 (30.5–40) | 2805/8097 | 42 | 50.5 (42.2–59) | 1336/2377 | 35 | 38.53 (4.5–45.5) | 5192/13,207 | 88 |
| Erythromycin | 70 (65–74) | 3952/5553 | 27 | 84 (79–88) | 1661/1977 | 26 | 73.7 (70–77) | 6969/10,874 | 69 |
| Penicillin | 18 (12–26.5) | 868/5382 | 26 | 85.5 (81–89) | 1656/1926 | 24 | 61 (55.5–66) | 2900/8437 | 66 |
| Chloramphenicol | 30 (23.3–38) | 543/1838 | 19 | 17.5 (11.5–26) | 113/657 | 14 | 26 (22.3–30) | 1355/5419 | 62 |
| Levofloxacin | 27.5 (22–34) | 1511/5045 | 17 | 79.3 (72.6–84.7) | 1182/1484 | 17 | 45 (40.7–49.6) | 4397/10,437 | 54 |
| Quinupristin/dalfopristin | 97 (89–99.2) | 2170/2479 | 9 | 8 (4.6–13.8) | 225/1972 | 23 | 44.5 (36–53) | 4435/7862 | 50 |
| Tetracycline | 81.5 (74.6–87) | 2822/3497 | 21 | 59 (49.2–68) | 651/1194 | 16 | 66 (62–70) | 4951/7028 | 48 |
| Daptomycin | 0.2 (0.1–0.5) | 0/3636 | 11 | 0.6 (0.2–1.2) | 0/1308 | 12 | 0.4 (0.3–0.6) | 2/8704 | 40 |
| Nitrofurantoin | 2 (0.8–5.6) | 77/2494 | 14 | 43 (30.5–56.7) | 455/1003 | 14 | 21.5 (15.7–28.5) | 703/4401 | 33 |
| Amoxicillin/clavulanic acid | 3.2 (0.5–18.5) | 8/400 | 5 | 54 (35–72) | 110/207 | 5 | 29.5 (19.5–41.5) | 183/976 | 19 |
| Imipenem | 5 (0.6–21.2) | 119/1076 | 6 | 79.3 (57.2–91.7) | 548/669 | 5 | 45 (25.5–66) | 731/2327 | 16 |
| Tigecycline | 0.5 (0.1–1.7) | 1/738 | 4 | 1 (0.2–4.5) | 3/492 | 4 | 0.5 (0.2–1) | 4/3404 | 11 |
| Norfloxacin | 23.5 (13–38.6) | 122/434 | 3 | 70.3 (40.89.3) | 114/144 | 3 | 57.3 (49.6–64.7) | 446/902 | 10 |
| Amikacin | 21.5 (17–27.3) | 51/236 | 2 | 31 (20.5–45.5) | 19/62 | 2 | 23.3 (19–28.3) | 133/633 | 10 |
| Linezolid | 0.9 (0.1–7) | 1/537 | 4 | 0.9 (0.2–4.3) | 0/172 | 3 | 1 (0.1–2.7) | 2/834 | 9 |