Table 3.
Prevalence of antibiotic resistance in blood-isolated Enterococcusspp. by study time groups
| Study year | 2000–2005 | 2005–2010 | 2010–2016 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Antibiotic | Pooled prevalence (%) (95% CI) | n/N | N of studies | Pooled prevalence (%) (95% CI) | n/N | N of studies | Pooled prevalence (%) (95% CI) | n/N | N of studies |
| Enterococcus faecalis | |||||||||
| Vancomycin | 1 (0.5–2) | 52/5148 | 25 | 2.2 (1.5–3.2) | 199/6401 | 37 | 2.7 (1.5–5) | 85/3084 | 24 |
| Gentamicin | 36.5 (28.5–45.5) | 1476/3790 | 21 | 39.7 (34–45.5) | 1910/4905 | 23 | 34.5 (30–39) | 3726/11,360 | 43 |
| Ampicillin | 4 (1.7–9) | 521/3753 | 17 | 2 (0.7–6) | 143/4832 | 14 | 9 (4–21) | 257/2354 | 15 |
| Teicoplanin | 0.9 (0.4–2) | 7/1468 | 9 | 1.8 (0.9–36) | 160/4020 | 19 | 4.4 (2.5–8) | 55/1472 | 13 |
| Linezolid | 0.3 (0.1–0.8) | 1/1543 | 6 | 0.4 (0.1–1) | 14/5020 | 15 | 2 (0.8–5.5) | 43/2180 | 13 |
| Enterococcus faecium | |||||||||
| Vancomycin | 8.2 (5–12.5) | 166/1861 | 24 | 9 (6.5–12.5) | 1232/9674 | 62 | 22 (14–33) | 364/1121 | 21 |
| Gentamicin | 42.5 (28–58.5) | 547/1447 | 20 | 44 (34–54) | 806/1648 | 20 | 57.5 (42–72.5) | 642/1062 | 12 |
| Ampicillin | 74.5 (65–82.5) | 826/1116 | 16 | 81 (75–85.5) | 1404/1692 | 17 | 76.5 (62–87) | 712/900 | 11 |
| Teicoplanin | 11.2 (7–17.7) | 44/454 | 9 | 13 (6.5–25.5) | 257/1177 | 15 | 24.5 (12–43.5) | 187/576 | 11 |
| Linezolid | 0.8 (0.3–2.2) | 0/709 | 7 | 1.6 (0.9–2.8) | 14/1722 | 17 | 3 (1–8) | 20/862 | 10 |