Table 1.
Characteristics associated with multi-drug resistant Enterobacteriaceae infection in neonates
| Variable | Babies with MDRE sepsis n/N (%) | Babies without sepsis n/N (%) | p value |
|---|---|---|---|
| Inborn | 196/288 (68.1) | 1716/2096 (81.9) | < 0.001 |
| Attended antenatal care | 188/254 (74.0) | 1663/1971 (84.4) | < 0.001 |
| Maternal chorioamnionitis | 7/238 (2.9) | 47/1875 (2.5) | 0.689 |
| Maternal HIV | 108/279 (38.7) | 600/2009 (29.9) | 0.003 |
| Vaginal Delivery | 134/261 (51.3) | 902/2076 (43.4) | 0.016 |
| Male | 157/291 (54.0) | 1113/2135 (52.1) | 0.697 |
| Multiple gestation | 44/284 (15.5) | 267/2078 (12.8) | 0.216 |
| Resuscitation at birth | 112/269 (41.6) | 451/2086 (21.6) | < 0.001 |
| Oxygen on day 28 | 118/262 (45.0) | 161/1957 (8.2) | < 0.001 |
| Nasal CPAP | 168/191 (87.9) | 961/2146 (44.8) | < 0.001 |
| Mechanical ventilation | 85/196 (43.4) | 791/2101 (37.6) | 0.115 |
| Necrotising enterocolitis (Grade 2 and 3) | 61/288 (21.2) | 164/2080 (7.9) | < 0.001 |
| Surgery (excluding necrotising enterocolitis)` | 45/284 (15.8) | 71/2065 (3.4) | < 0.001 |