Fig. 25.

Example standardized litre plots for genes that remained as kidney-specific DEGs after TMM normalization. Example standardized litre plots from the 1136 genes that were in the first cluster (Fig. 17) of genes that remained as kidney-specific DEGs even after TMM normalization. With standardization, we immediately note that meaningful information about the dataset as a whole (variation between treatments and replicates, normalization, sample mislabeling, and unexpected patterns like streaks) is now gone. In any case, we confirm that these standardized litre plots corroborate that these purple genes demonstrate the expected patterns of DEGs