Fig. 26.

Example standardized litre plots for genes that remained as liver-specific DEGs after TMM normalization. Example litre plots from the 933 genes that were in the first cluster (Fig. 18) from genes that remained as liver-specific DEGs even after TMM normalization. With standardization, we immediately note that meaningful information about the dataset as a whole (variation between treatments and replicates, normalization, sample mislabeling, and unexpected patterns like streaks) is now gone. In any case, we confirm that these standardized litre plots corroborate that these orange genes demonstrate the expected patterns of DEGs