Table 3.
Significantly different clinical and laboratory parameters of well * (Phe < 1200 μmol/l; n = 13) and poorly (Phe > 1200 μmol/l; n = 8) controlled patients
| Well controlled patients | Poorly controlled patients | ||
|---|---|---|---|
| mean ± SD | mean ± SD | p-value | |
| Phe μmol/l | 920.2 ± 163.4 | 1580.0 ± 254.3 | < 0.001 |
| Phe mean 5y - μmol/l | 829.3 ± 139.2 | 1247.0 ± 163.4 | < 0.001 |
| Total protein intake mean of 5y - g/kg/d | 1.0 ± 0.2 | 0.7 ± 0.0 | 0.022 |
| Age - years | 28.3 ± 8.7 | 35.3 ± 6.9 | 0.050 |
| BMI - kg/m2 | 24.0 ± 2.3 | 32.1 ± 5.3 | 0.001 |
| LDLc/HDLc | 1.9 ± 0.5 | 2.3 ± 0.5 | 0.025 |
| Triglycerides - mmol/l | 1.0 ± 0.4 | 1.9 ± 1.1 | 0.005 |
| Non-HDLc - mmol/l | 2.7 ± 0.4 | 3.2 ± 0.3 | 0.017 |
| HDL2c - mmol/l | 0.7 ± 0.3 | 0.5 ± 0.2 | n.s. |
| HDL2c/HDL3c | 0.9 ± 0.3 | 0.6 ± 0.3 | n.s. |
*according to the German PKU recommendations [23]