Table 4.

Lipoproteins, markers of inflammation and oxidative stress in patients and healthy controls

	PKU patients		Control group		p-value
	mean ± SD or median [IQR]	n	mean ± SD or median [IQR]	n
Lipids and Lipoproteins (mmol/l)
Total Cholesterol	4.3 ± 0.6	23	3.8 ± 0.6	28	0.003
LDLc	2.8 ± 0.7	23	2.6 ± 0.8	28	n.s.
HDLc	1.4 ± 0.3	23	1.6 ± 0.3	28	0.032
LDLc/HDLc	2.1 ± 0.5	23	1.7 ± 0.6	28	0.018
ApoA1 (mg/ml)	2.1 ± 0.7	23	1.8 ± 0.3	16	n.s.
HDL2c	0.6 ± 0.3	23	0.8 ± 0.2	28	0.009
HDL3c	0.8 ± 0.1	23	0.8 ± 0.1	28	n.s.
HDL2c/HDL3c	0.8 ± 0.3	23	1.1 ± 0.3	28	0.005
Non-HDLc	2.9 ± 0.4	23	2.2 ± 0.6	28	< 0.001
Triglycerides	1.3 ± 0.8	23	1.1 ± 0.6	28	n.s.
Phospholipids	2.7 ± 0.6	23	2.6 ± 0.4	28	n.s.
Markers of  Inflammation (mg/l)
SAA	6.7 [2.8–14.4]	22	2.9 [1.5–5.2]	27	0.010
CRP	18.4 [7.3–83.3]	22	6.3 [2.0–42.1]	27	0.010
Markers of Oxidative Stress
MDA (μg/ml)	0.33 [0.23–0.59]	23	0.23 [0.12–0.38]	27	0.027
MPO (μg/ml)	0.68 [0.29–0.97]	19	0.89 [0.34–1.3]	26	n.s.
3-NT (nmol/l)	1.8 [0.34–2.7]	22	1.7 [0.92–2.4]	28	n.s.