Table 1.
Univariate and multivariate analysis of the effect of variables on the risk of postoperative hypocalcemia
| Clinical factors | Normal (frequency/%) | Hypocalcemia (frequency/%) | Univariate | Multivariate | ||
|---|---|---|---|---|---|---|
| P | P | OR (95% CI) | ||||
| Gender | Male | 46/85.2 | 8/14.8 | <0.001 | <0.001 | 6.08 (2.39, 15.43) |
| Female | 103/54.8 | 85/45.2 | ||||
| Age | ≥55 | 23/62.2 | 14/37.8 | 0.94 | – | – |
| <55 | 126/61.5 | 79/38.5 | ||||
| Extent of surgery | UTL | 23/95.8 | 1/4.2 | <0.001 | 0.038 | 9.63 (1.31, 81.91) |
| TT | 126/57.8 | 92/42.2 | ||||
| CND | Unilateral | 42/73.7 | 15/26.3 | 0.03 | 0.734 | – |
| Bilateral | 107/57.8 | 78/42.2 | ||||
| LND | Yes | 21/40.4 | 31/59.6 | <0.001 | 0.008 | 2.99 (1.33, 6.71) |
| No | 128/67.4 | 62/32.6 | ||||
| VD deficiency | Yes | 50/57.5 | 37/42.5 | 0.33 | 0.184 | – |
| No | 99/63.9 | 56/36.1 | ||||
| Parathyroid number ≥3 | Yes | 117/61.6 | 73/38.4 | 1 | – | – |
| No | 32/61.5 | 20/38.5 | ||||
| Hypoparathyroidism | Yes | 53/43.1 | 70/56.9 | <0.001 | <0.001 | 4.23 (2.21, 8.35) |
| No | 96/80.7 | 23/19.3 | ||||
| Auto-T | Yes | 30/50.8 | 29/49.2 | 0.05 | 0.503 | - |
| No | 119/65.0 | 64/35.0 | ||||
| Hypomagnesemia | Yes | 18/37.5 | 30/62.5 | <0.001 | <0.001 | 4.66 (1.97, 11.02) |
| No | 131/67.5 | 63/32.5 | ||||
| Pre-Ca | 2.00–2.34 | 52/48.1 | 56/51.9 | <0.001 | 0.002 | 0.37 (0.20, 0.70) |
| 2.34–2.60 | 97/73.4 | 37/26.6 | ||||
| Pre-Mg/mmol L−1 | 0.88 (0.83, 0.93) | 0.87 (0.83, 0.91) | 0.53 | – | – | |
| Pre-PTH/pg mL−1 | 45.04 (34.75, 58.68) | 40.43 (31.48, 53.82) | 0.05 | – | – | |
Abbreviations: UTL, unilateral lobectomy; TT, total thyroidectomy; CND, central lymph node dissection; LND, lateral lymph node dissection; VD, vitamin D; Auto-T, autotransplantation; Pre, preoperative; Po, postoperative.