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. 2019 Sep 3;11:8167–8179. doi: 10.2147/CMAR.S209904

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© 2019 Yang et al.

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Upregulation of HOXC6 is associated with poor prognosis of patients with CBM. (A) H&E staining of HOXC6 protein expression in 14 normal brain tissue samples and 107 GBM tissues with anti-HOXC6 antibody. Two representative cases were shown. The scale bar of each figure is 50 μm. (B) Immunohistochemical staining of HOXC6 protein in 107 paired CBMs and their corresponding noncancerous tissues with anti-HOXC6 antibody. The scale bar of each figure is 50 μm. (C) HOXC6 overexpression was associated with OS (n=107, p=0.0243) and DFS (n=107, p=0.0013) according to Kaplan–Meier analysis.