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. 2019 Sep 3;12:7203–7214. doi: 10.2147/OTT.S194800

Figure 3.

Figure 3

Effect of miR-765 on DNA repair through APE1 inhibition. The number of γ-H2AX foci/cell was counted in a minimum of 200 cells per treatment group. The average number of γ-H2AX foci/cell is shown. Error bars indicate S.D. * p<0.05. (A and B) The representative images of 9901 cells transfected with miR-765 mimics or the miR NC and treated with cisplatin (5 ug/ml) from the 6 hr groups are shown. (C and D) The representative images of 9901 cells cotransfected with miR-765 mimics and siAPE1 (siNC) and treated with cisplatin (5 µg/ml) from the 6 hr groups are shown.