TABLE 1:

Pharmacokinetic parameters of 6 pregnant women 18–23 weeks’ after 200mg micronized vaginal progesterone. Serum progesterone sampled every two hours at hour zero (pre dose) over 12 hours post dose and then at 24 hours post dose. AUC: area under curve; Cmax: maximum concentration; Tmax: time to maximum concentration; IQR: interquartile range. Data presented as median [IQR].

Median Age (years)	27.0[21.5-33.3]
Median BMI(kg/m2)	26.5 [23.3-29.0]
Median Gestational Age (wk)	22.9 [21.0-23.4]
Median Baseline Serum Progesterone [IQR] (ng/ml)	47[40 to 52]
Median Cmax [IQR] (ng/ml)	54 [48 to 68]
Median Tmax [IQR] (hr)	12 [4 to 15]
Median ΔCmax from Baseline [IQR]	11 [2 to 22]
Median % change of ΔCmax from Baseline [IQR]	24 [4 to 53]
Median AUC [IQR] ng*h/ml	112 [−43 to 239]