The four OCT metrics included in the study measured pre- and post- allergen (right middle lobe) and diluent (right upper lobe) for each of the three groups. (a) Mucosal thickness. (b) Epithelial thickness. (c) Mucosal buckling. (d) mucus contrast. AA, allergic asthmatic; AC, allergic control; HC, healthy control; A.U, arbitrary units. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.