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. 2019 Aug;9(4):362–370. doi: 10.21037/cdt.2019.08.02

Table 3. Risk factors for CVD in patients with obstructive sleep apnea.

Independent variables All the subjects Obstructive sleep apnea
Odd ratio 95% CI P value Odd ratio 95% CI P value
Age (years) 1.048 1.025–1.071 <0.001* 1.048 1.023–1.074 <0.001*
Male gender 1.468 0.730–2.951 0.281 1.358 0.619–2.979 0.446
BMI (kg/m2) 1.005 0.960–1.053 0.818 1.005 0.957–1.056 0.835
AHI (events/h) 1.021 1.008–1.034 0.002* 1.026 1.011–1.041 <0.001*
Mean SpO2 (%) 0.923 0.798–1.067 0.278 0.936 0.804–1.089 0.390
LSpO2 (%) 0.991 0.967–1.016 0.483 0.989 0.963–1.015 0.411
TS90 (%) 1.014 0.987–1.041 0.327 1.015 0.987–1.044 0.304
MHR 1.187 1.130–1.246 <0.001* 1.190 1.128–1.256 <0.001*
Cigarette smoking 1.145 0.600–2.185 0.680 1.151 0.578–2.292 0.689
Hypertension 0.559 0.312–1.003 0.051 0.502 0.265–0.953 0.035*
Diabetes mellitus 0.759 0.434–1.328 0.334 0.867 0.474–1.585 0.643
Dyslipidemia 1.101 0.623–1.947 0.740 1.056 0.567–1.968 0.863

CVD, cardiovascular disease; BMI, body mass index; AHI, apnea-hypopnea index; Mean SpO2, mean oxygen saturation; LSpO2, lowest pulse oxygen saturation; TS90, the percentage of sleep duration with SpO2 <90%; MHR, monocyte to high-density lipoprotein cholesterol ratio. *P<0.05: statistical significance.