Table 3. Risk factors for CVD in patients with obstructive sleep apnea.
Independent variables | All the subjects | Obstructive sleep apnea | |||||
---|---|---|---|---|---|---|---|
Odd ratio | 95% CI | P value | Odd ratio | 95% CI | P value | ||
Age (years) | 1.048 | 1.025–1.071 | <0.001* | 1.048 | 1.023–1.074 | <0.001* | |
Male gender | 1.468 | 0.730–2.951 | 0.281 | 1.358 | 0.619–2.979 | 0.446 | |
BMI (kg/m2) | 1.005 | 0.960–1.053 | 0.818 | 1.005 | 0.957–1.056 | 0.835 | |
AHI (events/h) | 1.021 | 1.008–1.034 | 0.002* | 1.026 | 1.011–1.041 | <0.001* | |
Mean SpO2 (%) | 0.923 | 0.798–1.067 | 0.278 | 0.936 | 0.804–1.089 | 0.390 | |
LSpO2 (%) | 0.991 | 0.967–1.016 | 0.483 | 0.989 | 0.963–1.015 | 0.411 | |
TS90 (%) | 1.014 | 0.987–1.041 | 0.327 | 1.015 | 0.987–1.044 | 0.304 | |
MHR | 1.187 | 1.130–1.246 | <0.001* | 1.190 | 1.128–1.256 | <0.001* | |
Cigarette smoking | 1.145 | 0.600–2.185 | 0.680 | 1.151 | 0.578–2.292 | 0.689 | |
Hypertension | 0.559 | 0.312–1.003 | 0.051 | 0.502 | 0.265–0.953 | 0.035* | |
Diabetes mellitus | 0.759 | 0.434–1.328 | 0.334 | 0.867 | 0.474–1.585 | 0.643 | |
Dyslipidemia | 1.101 | 0.623–1.947 | 0.740 | 1.056 | 0.567–1.968 | 0.863 |
CVD, cardiovascular disease; BMI, body mass index; AHI, apnea-hypopnea index; Mean SpO2, mean oxygen saturation; LSpO2, lowest pulse oxygen saturation; TS90, the percentage of sleep duration with SpO2 <90%; MHR, monocyte to high-density lipoprotein cholesterol ratio. *P<0.05: statistical significance.