Table 3. Multivariable associations of baseline variables with change in LCBI (n=47).
Parameter | β coefficient | 95% CI | standardized β | P value |
---|---|---|---|---|
Baseline LCBI | −0.24 | [−0.45, −0.03] | −0.31 | 0.02 |
Follow-up period | 0.04 | [−0.07, 0.15] | 0.11 | 0.47 |
Clinical presentation of CAD | 306.22 | [109.95, 502.49] | 2.31 | 0.003 |
ABCG1 CEC without clinical presentation of CAD | 10.39 | [−21.72, 42.51] | 0.11 | 0.52 |
ABCG1 CEC with clinical presentation of CAD | −76.92 | [−126.41, −27.44] | −0.79 | 0.003 |
A plus value of β coefficient, with concomitant P value less than 0.05, indicates that the variable is positively associated with change in coronary lipid burden; A minus value of β coefficient, with concomitant P value less than 0.05, indicates that the variable is negatively associated with change in coronary lipid burden. ABCG1 CEC, ATP-binding cassette transporter G1-mediated cholesterol efflux capacity; CAD, coronary artery disease; CI, confidence interval; LCBI, lipid core burden index.