Table S7. Comparisons of characteristics and lipid-related parameters according to clinical presentation (n=47).
| Parameter | Stable ischemic symptoms (n=31) | Acute coronary syndrome (n=16) | P value |
|---|---|---|---|
| Age, years | 59 [53, 71] | 62 [54, 70] | 0.92 |
| Female, n [%] | 11 [35] | 3 [19] | 0.32 |
| Current smoker, n [%] | 6 [19] | 5 [31] | 0.47 |
| Diabetes, n [%] | 11 [35] | 3 [19] | 0.32 |
| Hypertension, n [%] | 22 [71] | 10 [63] | 0.74 |
| Dyslipidemia, n [%] | 24 [77] | 12 [75] | 1.00 |
| Medication, n [%] | |||
| Aspirin | 27 [87] | 16 [100] | 0.28 |
| ACE-I/ARB | 19 [61] | 12 [75] | 0.52 |
| Statin | 21 [68] | 15 [94] | 0.07 |
| HIST | 9 [29] | 14 [88] | <0.001 |
| Beta-blocker | 8 [26] | 11 [69] | 0.01 |
| Lipids, mg/dL | |||
| T-Cho | 178 [128, 197] | 159 [147, 191] | 0.76 |
| LDL-C | 108 [81, 135] | 89 [72, 104] | 0.30 |
| HDL-C | 43 [35, 50] | 41 [31, 44] | 0.92 |
| TG | 124 [80, 168] | 142 [106, 190] | 0.78 |
| HDL-mediated cholesterol efflux capacity, % | |||
| ABCA1 CEC | 22.9 [20.8, 25.2] | 22.3 [20.4, 24.7] | 0.97 |
| ABCG1 CEC | 3.4 [3.0, 4.1] | 3.3 [3.2, 4.0] | 0.82 |
| SR-BI CEC | 10.6 [9.6, 12.3] | 10.5 [9.4, 11.7] | 0.93 |
| NIRS parameters | |||
| Baseline LCBI | 42 [4, 109] | 79 [45, 153] | 0.20 |
Continuous variables are expressed median [interquartile range], and categorical variables as percentage. ACE-I, angiotensin converting enzyme inhibitor; ARB, angiotensin II receptor blocker; HDL-C, high-density lipoprotein cholesterol; HIST, high-intensity statin therapy; LCBI, lipid core burden index; LDL-C, low-density lipoprotein cholesterol; NIRS, near-infrared spectroscopy; T-Cho, total cholesterol; TG, triglyceride.