Fig. 3.

The loss of CLDN10 inhibited the proliferation and metastasis of OS cell line. a The effects of CLDN10 knockout and the activation of the JAK1/Stat1 signaling pathway (left), and the corresponding statistical analysis of protein expression (right). Note: normalized with β-actin, **P < 0.01, versus scramble group. b Growth curve of MG63 cells. c The abilities of MG63 cells to form colonies. d The impact of CLDN10 knockout on the invasive ability of MG63 cells in vitro (left), and the corresponding statistical analysis (right). e The impact of CLDN10 knockout on the migration ability of MG63 cells in vitro. ^**P < 0.01, versus the scramble group