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. Author manuscript; available in PMC: 2019 Sep 8.
Published in final edited form as: Inhal Toxicol. 2017 Aug 17;29(6):266–281. doi: 10.1080/08958378.2017.1357774

Figure 8.

Figure 8.

MVE-exposure mediates increased expression of adhesion and cytokine molecules, which is mediated via LOX-1 receptor signaling. RT-qPCR analysis of in the cerebral microvessels of (A) intracellular adhesion molecule (ICAM)-1; (B) vascular cell adhesion molecule (VCAM)-1; and (C) monocyte chemoattractant protein (MCP)-1 in ApoE−/− mice exposed to either filtered air (FA)+ IgG; FA + LOX-1 Ab (16 mg/ml, 0.1 ml/mouse, every other day throughout exposure); 100 PM μg/m3 of mixed vehicular emission (MVE) + IgG; or MVE + LOX-1 Ab for 6 h/d, 7 d/week, for 30 d. *p < 0.050 compared to FA control, †p < 0.050 compared to MVE + IgG, as determined by ANOVA.