Table 4.
IL10 haplotype frequencies in frail and nonfrail
Haplotypes | Block |
Frail (n = 307) |
Nonfrail (n = 368) |
OR (95% CI) | p‐value |
---|---|---|---|---|---|
H1 | ACA | 0.201 | 0.257 | 0.725 (0.560–0.938) | .014 |
H2 | ATG | 0.164 | 0.209 | 0.744 (0.564–0.982) | .036 |
H3 | ATA | 0.154 | 0.205 | 0.718 (0.542–0.952) | .021 |
H4 | ACG | 0.164 | 0.061 | 3.023 (2.089–4.374) | <.001 |
H5 | CTG | 0.101 | 0.074 | 1.418 (0.968–2.078) | .071 |
H6 | CCA | 0.070 | 0.075 | 0.931 (0.615–1.408) | .734 |
H7 | CTA | 0.067 | 0.076 | 0.869 (0.572–1.320) | .509 |
H8 | CCG | 0.077 | 0.042 | 1.885 (1.182–3.006) | .007 |
The order of the polymorphisms in the haplotypes is according to the positions in the chromosome (rs1800872, rs1800871 and rs1800896).
Construct eight haplotypes.
Bold numbers indicate significant associations.
Abbreviations: 95% CI, confidential interval; OR, odds ratio.