Figure 4.

Behavioral characteristics of mAS patients contrasted to typical AS patients identified as part of the Angelman Syndrome Natural History trial. Behavioral characteristics occurring in greater than 25% of mAS patients (a). Behaviors present in AS patients but not reported in mAS patients (b). *p < 0.05, **p < 0.01 by Fisher's exact test. Neuropsychological and language raw scores from mAS and AS patients from between 4–6 years of age (c and d). n = 3–4 for mAS, n = 126–202 for AS. *p < 0.05, **p < 0.01 by Student's t test or one‐sample t test