Table 1.
Clinical characteristics of each group
| Control | CAD | DM2‐CAD | |
|---|---|---|---|
| Gender (M/F) | 63 (30/33) | 79 (42/37) | 59 (28/31) |
| Age (years) | 56 ± 9.6 | 61 ± 10.8 | 59 ± 11.7 |
| FG (mmol/L) | 4.95 ± 0.85 | 9.12 ± 2.21** | 11.67 ± 2.72** |
| HbA1c (%) | 3.18 ± 1.3 | 7.55 ± 7.9** | 10.1 ± 6.9** |
| Hemoglobin (g/dl) | 12.87 ± 1.6 | 13.71 ± 1.9 | 12.45 ± 2.1 |
| WBC (×109/L) | 8.1 ± 4.1 | 7.7 ± 2.7 | 7.9 ± 3.9 |
| Platelet count (×109) | 269 ± 50.6 | 251 ± 64.5 | 259 ± 62.8 |
| MPV (fL) | 9.97 ± 1.06 | 10.9 ± 1.14* | 11.2 ± 1.26* |
| Diabetes duration (years) | ‐ | 14.5 ± 5.5** | 20.8 ± 8.3** |
| BMI (kg/m2) | 23.2 ± 4.1 | 26.4 ± 3.8* | 27.2 ± 5.1* |
| Smoking (%) | 15 (23.80) | 17 (21.51) | 16 (27.11) |
| Hypertension (%) | 23 (36.50) | 24 (30.37) | 21 (35.59) |
| Hyperlipidemia (%) | 20 (31.74) | 25 (31.64) | 22 (37.29) |
| Mean BP (mmHg) | 85.4 ± 2.7 | 89.5 ± 9.4* | 95.2 ± 7.7* |
| LDL‐C (mmol/L) | 2.38 ± 0.7 | 2.98 ± 1.3* | 5.35 ± 1.5** |
| HDL‐C (mmol/L) | 1.38 ± 0.4 | 1.10 ± 0.29 | 0.88 ± 0.38* |
| TC (mmol/L) | 4.08 ± 0.9 | 4.81 ± 1.8* | 7.15 ± 2.4** |
| TG (mmol/L) | 1.48 ± 0.6 | 1.55 ± 0.8 | 2.48 ± 1.08** |
| ACR (mg/mmol) | 0.67 ± 0.28 | 0.88 ± 0.34 | 0.94 ± 0.57* |
| Serum creatinine (μm/L) | 54.7 ± 10.8 | 59.1 ± 13.9 | 64.8 ± 15.3 |
| eGFR (ml/min/1.73m2) | 103 ± 13.4 | 102 ± 11.5 | 104 ± 12.2 |
Data are presented as number (percentage) for categorical data or mean ± standard deviation (SD) for parametrically distributed data.
Abbreviations: ACR: albumin/creatinine ratio; BMI, body mass index; BP, blood pressure; CAD, coronary artery disease; DM2, type 2 diabetes mellitus; eGFR, estimated glomerular filtration rate; FG, fasting glucose; HbA1c, glycated hemoglobin; HDL‐C, high‐density lipoprotein cholesterol; LDL‐C, low‐density lipoprotein cholesterol; MPV, mean platelet volume; TC, total cholesterol; TG, triglyceride; WBC, white blood cell.
*
p < .05,
**
p < .01 compared to control group.