Table 1. Primer sequences used in reverse transcription quantitative PCR.

Gene	Primer sequence (5′→3′)
GAPDH	F: AAG GTG AAG GTC GGA GTC A
	R: GGA AGA TGG TGA TGG GAT TT
MMP-1	F: AGT GTG TCA CCA TAC CAA GCA C
	R: CGA GGC ACC AAG ACT GGA AGA
MMP-3	F: CAA GGG CCT CTT CTG CGA TTT CG
	R: CGG TAG GCA GCT AGG GCA GGG C
MMP-9	F: GTC CCA CCC ACC CCA GAC AGA
	R: GAG CCA CAA ACT GCA GGT GGT
ADAMTS-4	F: GAT CGA TGC CGG TGC TAA GA
	R: TCC TAT GGG AGA ACG GCA GA
ADAMTS-5	F: CTT CGG CAG CAC ATA TAC
	R: GAA CGC TTC ACG AAT TTG C
collagen Ⅱ	F: TGC AGG CTG GAG ATC CTA CT
	R: TTC TAG ACG GCA GGT CAG GT
aggrecan	F: AGG CTG AAG TTA CAG GTC
	R: TTG GCT CCC AGT GTC TTA
miR-16-5p	F: CAG TGC GTG TCG TGG AGT
	R: AGG TCC AGT TTT CCC AGG
SNHG1	F: AGG CTG AAG TTA CAG GTC
	R: TTG GCT CCC AGT GTC TTA