Table 4.
Preplacentation Reactome Pathway Gene Set Enrichment Analysis
| Pathway | Genes | P value |
|---|---|---|
| Day 7 | ||
| Fatty acid metabolism | Acot5/Acot6/Cyp4b1/Acads/Acot7 | 0.00331 |
| Posttranslational modification: synthesis of GPI-anchored proteins | Msln/Lypd1/Pgap1/Vnn1 | 0.003386 |
| Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein | St6 galnac2/Pmm1/Nans/St3 gal6 | 0.00552 |
| Synthesis of substrates in N-glycan biosynthesis | St6 galnac2/Pmm1/Nans/St3 gal6 | 0.00552 |
| Metabolism of water-soluble vitamins and cofactors | Slc19a3/Slc5a8/Slc52a3/Vnn1 | 0.016794 |
| Metabolism | Slc19a3/Acot5/Dcxr/Acot6/Slc5a8/Slc22a1/Pla2 g2a/Cyp4b1/Slc52a3/Bdh1/Acads/Acot7/Plcd3/Alad/Vnn1/Etfa/Idi1/St3 gal6 | 0.022344 |
| Posttranslational protein phosphorylation | Msln/Fgg/Spp1 | 0.026206 |
| Transport of inorganic cations/anions and amino acids/oligopeptides | Slc26a3/Slc5a8/Slc15a2 | 0.036759 |
| Day 10 | ||
| Glycerophospholipid biosynthesis | Osbpl8/Pla2 g16/Cept1/Pld1 | 0.002969 |
| Phospholipid metabolism | Osbpl8/Pla2 g16/Cept1/Pld1 | 0.008546 |
| Metabolism of lipids | Cyp2e1/Hpgd/Osbpl8/Pla2 g16/Ppt1/Cept1/Pld1 | 0.008658 |