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Relationship between mean arterial pressure (MAP) increase (MAPIncrease) and heart rate (HR) decrease (HRDecrease) following a spontaneous muscle sympathetic nerve activity (MSNA) burst in nonsmokers (R = −0.719, P < 0.001; ○, n = 42) and smokers (R = −0.206, P = 0.413; ●, n = 18). Slope of the regression line was significantly smaller in smokers than nonsmokers (−0.206 vs. −1.104 beats·min−1·mmHg−1, P = 0.004).
