Fig. 13.

Oral glucose tolerance test (OGTT) glucose and insulin responses for individuals with initial abnormal glucose tolerance in the placebo and DHEA supplementation groups. The reduction in glucose area under the curve (AUC) in the DHEA group (C) was significantly greater than that for the placebo group (A; P = 0.03). Changes in the insulin AUC did not differ between groups (B and D; P = 0.52). Improvements in glucose AUC were maintained in a subset of DHEA group participants who completed a 2nd yr of DHEA supplementation (E; P < 0.05 for baseline vs. DHEA). *P < 0.05 for baseline versus DHEA. [Reproduced from Weiss et al. (184) under Creative Commons Attribution License 3.0. Copyright Weiss et al. (184).]