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. 2019 Sep 8;7(17):e14200. doi: 10.14814/phy2.14200

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© 2019 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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No overt damage induced by massage in young and old muscle. IgG (green) staining of tibialis anterior muscle after down‐hill running (A) demonstrating IgG infiltration into injured fibers (yellow arrows). Additional fibers exhibiting moderate to low IgG infiltration did not meet the criteria for injury (white arrows). Representative cross sections of gastrocnemius muscles immunoreacted for IgG from: (B) 10C; (C) 10M; (D) 30C; and (E) 30M. Bar graph depicting IgG mean intensity of fibers from controls (C) and massaged (M) groups of young (10 month) and old (30 month) rats (F). Bars indicate mean ± SE. There were no significant differences in IgG mean intensity.