Table 2.
Univariable analysis of baseline characteristics
| Variable | No AKI (n=73) | AKI (n=65) | Odds ratio (95% CI) | p-value | Survival within 30 days (n=94) | Nonsurvival (n=44) | Odds ratio (95% CI) | p-value |
|---|---|---|---|---|---|---|---|---|
| Age (years) | 65.0 (55.0–78.5) | 71.0 (60.5–82.0) | 1.021 (1.000–1.044) | 0.054 | 66.5 (56.0–79) | 71.5 (61.3–82.8) | 1.025 (1.000–1.050) | 0.047 |
| Male sex | 43 (31) | 42 (30) | 1.274 (0.639–2.540) | 0.491 | 56 (60) | 29 (66) | 1.312 (0.621–2.769) | 0.476 |
| Hypertension | 21 (15) | 34 (25) | 0.368 (0.182–0.743) | 0.005 | 37 (39) | 18 (41) | 1.067 (0.514–2.212) | 0.863 |
| CCI | 1.0 (0.0–2.0) | 1.0 (0.0–2.0) | 1.225 (0.975–1.540) | 0.082 | 1.0 (0.0–2.0) | 2.0 (0.25–2.0) | 1.310 (1.039–1.652) | 0.022 |
| PCT (ng/mL) | 11.1 (2.8–48.8) | 24.3 (7.3–100.0) | 1.013 (1.003–1.022) | 0.009 | 15.1 (5.0–55.8) | 18.0 (2.8–88.0) | 1.003 (0.994–1.013) | 0.502 |
| NT-proBNP (pg/mL) | 1150.0 (391.0–2663.5) | 3792.0 (1214.5–9115.0) | 1.117 (1.040–1.199) | 0.002 | 1716.0 (447.5–3640.0) | 3746.0 (1258.0–13,848.0) | 1.042 (1.042–1.170) | 0.001 |
| SCr (μmol/L) | 68.0 (52.0–82.5) | 174.0 (94.0–203.0) | 1.043 (1.028–1.059) | <0.001 | 77.0 (56.0–129.8) | 116.0 (75.8–197.8) | 1.009 (1.004–1.015) | 0.001 |
| Lac (mmol/L) | 2.7 (1.6–3.4) | 3.6 (2.3–5.8) | 1.181 (1.038–1.343) | 0.011 | 2.8 (1.6–3.7) | 4.0 (2.3–6.8) | 1.240 (1.088–1.412) | 0.001 |
| SOFA score | 9.0 (7.0–11.0) | 12.0 (10.0–15.0) | 1.478 (1.263–1.729) | <0.001 | 9.0 (8.0–11.0) | 12 (10.3–15.8) | 1.493 (1.273–1.752) | <0.001 |
| APACHE II score | 15.5 (13.0–21.0) | 23.0 (19.0–27.8) | 1.170 (1.097–1.249) | <0.001 | 16.0 (14.0–21.0) | 24.5 (20.0–28.8) | 1.170 (1.095–1.249) | <0.001 |
| Cumulative fluid balance (mL) | 2715.0 (1660.0–3579.0) | 3500.0 (2042.5–5050.0) | 1.290 (1.079–1.542) | 0.005 | 2805.0 (1707.5–3592) | 4050 (2658.8–5516.3) | 1.490 (1.213–1.831) | <0.001 |
| RRT | 5 (4) | 26 (19) | 0.110 (0.039–0.310) | <0.001 | 8 (9) | 23 (52) | 0.085 (0.033–0.216) | <0.001 |
| Ventilation duration | 3.4 (1.2–9.3) | 6.6 (2.7–12.6) | 1.014 (0.979–1.050) | 0.441 | 4.3 (1.5–9.8) | 4.5 (2.6–11.8) | 0.991 (0.954–1.030) | 0.645 |
| Length of ICU stay | 5.0 (2.6–10.7) | 7.6 (3.4–14.9) | 1.014 (0.980–1.049) | 0.415 | 6.5 (3.0–13.7) | 5.4 (2.7–14.0) | 0.975 (0.936–1.016) | 0.234 |
Notes: Continuous variables with normal distribution are presented as the mean ± standard deviation (SD), continuous variables with non-normally distribution are presented as the median (interquartile range (IQR) and categorical variables are presented as n (%).
Abbreviations: CCI, Charlson Comorbidity Index; PCT, serum procalcitonin; NT-proBNP, serum N-Terminal pro-brain natriuretic peptide; SCr, serum creatinine; Lac, serum lactate; SOFA score, Sequential Organ Failure Assessment score; APACHE II score, Acute Physiology and Chronic Health Evaluation II score; RRT, renal replacement therapy; ICU, intensive care unit.