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. 2019 Sep 4;12:7227–7241. doi: 10.2147/OTT.S219056

Figure 1.

Figure 1

The hypoxia-related signal pathway, Cluster 1 genes, and their potential molecular-targeted medicines.

Abbreviations: HIF, hypoxia-inducible factor; VEGF, vascular endothelial growth factor; PHD2, prolyl hydroxylase domain protein 2; SDH, succinate dehydrogenase; IDH, isocitrate dehydrogenase; FH, fumarate hydratase; VHL, von Hippel Lindau.