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. 2019 Sep 4;12:7227–7241. doi: 10.2147/OTT.S219056

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© 2019 Liu et al.

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The increased kinase signal pathways, Cluster 2 genes, and their potential molecular-targeted medicines.

Abbreviations: VEGF, vascular endothelial growth factor; VEGFR, vascular endothelial growth factor receptor; PDGF, platelet-derived growth factors receptor; MAX, myc-associated factor X; TMEM127, transmembrane protein 127; NF1, neurofibromin 1; KIF1Bβ, kinesin family member1B β; RET, rearranged during transfection proto-oncogene; FGFR1, fibroblast growth factor receptor 1; MET, MET proto-oncogene; PI3K, phosphatidylinositol 3-kinase; mTOR, mammalian target of rapamycin; MEK, MAPK/ERK kinase; ERK, extracellular regulated protein kinases; HSP, heat shock protein.