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. 2019 Sep 4;12:183–204. doi: 10.2147/IJNRD.S215370

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© 2019 Raina et al.

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The alternative complement pathway in atypical hemolytic uremic syndrome and the associated genetic mutations.

Note: Data from references 3, 16, 18-25.

Abbreviations: CFB, complement factor B; CFD, complement factor D; CFI, complement factor I; CFH, complement factor H; MCP, membrane cofactor protein; THBD, thrombomodulin; MAC, membrane attack complex; CFHR, complement factor receptor; PLG, plasminogen; INF2, Inverted Formin 2; aHUS, atypical hemolytic uremic syndrome.