Skip to main content
. 2019 Aug 25;2019:7281462. doi: 10.1155/2019/7281462

Table 4.

Effects of a Th1/17-biased environment on mRNA responses of primary AECs to virus-like/bacterial stimuli.

Cytokines LPS Imiquimod Poly I:C
IL6 ns
CXCL8 ns
TNF ns ns
IL1β ns ns ∗∗∗
IFN-β1 ns ns ns

Table 4 summarizes the change in gene expression in AEC cultured in the presence of Th1/17 cytokines, relative to cells grown in media alone, following stimulation with LPS, imiquimod, and poly I:C, respectively (n = 7 for each group). The significant differences compared to cells cultured in media alone are shown as p < 0.05 and ∗∗∗p < 0.001. For example, first “↑” in the table represents that the increase in the expression of mRNA for IL6 in response to LPS was significantly greater in AEC cultured in a Th1/17-biased environment than the increase in the expression of mRNA for IL6 in response to LPS in AECs grown in the absence of Th1/17 cytokines.