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. 2019 Aug 27;2019:5893028. doi: 10.1155/2019/5893028

Table 1.

The summarization of the relationship between gut microbiota and circadian clock.

Conditions Gut microbiota Circadian clock Reference
Jet lag Loss of oscillations in Ruminococcaceae Bmal, Rev-erbα, and RORγt [66]
High-fat, high-sugar diet Increase in ratio of Firmicutes/Bacteriodetes and Ruminococcus Per2 [69]
Cyanobacteria Synechococcus elongatus PCC 7942 kaiA, kaiB, and kaiC [70]
Human Enterobacter aerogenes Melatonin [72]
Antibiotic treatment or germ-free mice Antibiotic-induced gut microbial alterations or the absence of gut microbes RORα, RevErbα, Bmal1, Cry1, Per1, and Per2 [73, 74]
Fecal transplantation from high-fat-diet-fed donors Increase in Firmicutes and decrease in Bacteriodetes Bmal1, Per2, Rev-erba, and Dbp [75]