Table 5.
Correlation between different genotypes of FokI SNP with the expression of total vitamin D, 25(OH)D3, and calcium serum levels in patients and controls.
| Biochemical test | Patients (n=50) | Controls (n=50) | P value | ||||
|---|---|---|---|---|---|---|---|
| Frequency (%) | Frequency (%) | ||||||
| FF | Ff | ff | FF | Ff | ff | ||
| 33 (66%) | 13 (26%) | 4 (8%) | 24 (48%) | 23 (46%) | 3 (6%) | ||
| Total vitamin D (nmol/L) | 91.62±13.49 | 79.15±11.75 | 91.89±26.26 | 154.0±16.46 | 136.20±14.21 | 109.0±11.36 | 0.0013 |
| P value | 0.87 | 0.57 | |||||
|
| |||||||
| 25(OH)D3 (nmol/L) | 33.00±2.69 | 32.69±3.00 | 36.00±6.88 | 42.83±2.62 | 33.48±2.98 | 28.00±9.02 | 0.06 |
| P value | 0.82 | 0.02 | |||||
|
| |||||||
| Calcium (mmol/L) | 2.22±0.029 | 2.21±0.023 | 2.19±0.058 | 2.33±0.018 | 2.31±0.019 | 2.22±0.095 | 0.0012 |
| P value | 0.39 | 0.30 | |||||
P value was calculated by Kruskal-Wallis test with Dunn's multiple comparison.