Effect of sustained hypoxemia (HOX) on fetal endocrine milieu. Fetal arterial plasma insulin (A), norepinephrine (B), cortisol (C), and glucagon (D) concentrations were measured. Data were analyzed by 2-way ANOVA with fixed effects of treatment (HOX), day (DAY), and the interaction (INT). For post hoc analysis: *differences between control (CON) and HOX within a day of study; #HOX means are different between days 4 and 9. Individual data points with group means ± SE are shown (n = 2 male and 5 female CON fetuses and 8 male, 5 female HOX fetuses).