Table 2.
Comparison of hypomagnesemia in HNF1B mut+ and mut− groups
| Age (yr) | HNF1B mutation | Hypomagnesemia patients, n (%) | Normomagnesemia patients, n (%) | Fisher’s exact comparison |
|---|---|---|---|---|
| 0–4.5 | + | 4 (22) | 14 (78) | P = 0.26 |
| − | 2 (4) | 51 (96) | ||
| 4.5–9.0 | + | 5 (50) | 5 (50) | P = 0.18 |
| − | 9 (23) | 30 (77) | ||
| 9.0–13.5 | + | 9 (90) | 1 (10) | P = 0.0001a |
| − | 5 (17) | 25 (83) | ||
| 13.5–18.0 | + | 5 (100) | 0 (0) | P = 0.02a |
| − | 3 (16) | 16 (84) |
Shown are the number (n) and percentage (%) of patients with hypomagnesemia by age group and HNF1B mutation status. The Fisher exact test compares the number of patients with hypomagnesemia across the mutation groups. Note that the frequency of hypomagnesemia increases with age and the difference between mutation groups becomes significant in the second half of childhood. Also note that individual patients may be represented in more than 1 age group, if their follow-up extended beyond this age group.
a
Significant (P < 0.05) values.