. 2019 Aug 22;4(10):14234–14241. doi: 10.1021/acsomega.9b01640

Table 1. Preparation of Biphenyl under Different Conditions^a.

entry	solvent	FLA-Pd (g)	base	T (°C)	time (min)	yield (%)^b
1	THF	0.05	K₂CO₃	reflux	120	65
2	toluene	0.05	K₂CO₃	reflux	120	42
3	H₂O	0.05	–	rt	240	0
4	H₂O	0.05	–	reflux	240	0
5	EtOH	0.05	K₂CO₃	reflux	60	70
6	H₂O	0.05	K₂CO₃	reflux	60	93
7	H₂O	0.05	NaOAc	reflux	120	50
8	H₂O	0.05	NaHCO₃	reflux	120	76
9	H₂O	0.05	Et₃N	reflux	120	61
10	H₂O	0.05	n-Pr₃N	reflux	120	62
11	H₂O	0.03	K₂CO₃	reflux	120	70
12	H₂O	0.07	K₂CO₃	reflux	60	93

Reaction conditions: PhI (1.0 mmol); PhB(OH)₂ (1.1 mmol); base (2.0 mmol); solvent (10.0 mL).

Isolated yield of the pure product.

Table 1. Preparation of Biphenyl under Different Conditionsa.