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. 2019 Sep 5;18:1533033819870781. doi: 10.1177/1533033819870781

Figure 5.

Figure 5.

Inhibition effect of curcumin in CRC is mediated by NBR2. A and B, MTT assay revealed the proliferation of HCT116 and SW480 cells after treatment with 0 or 10 μM curcumin for 24 hours. C and D, Clone formation in curcumin-treated HCT116 and SW480 cells after shNBR2 transfection and treated with 0 or 10 μM curcumin for 24 hours. E and F, BrdU assay showed the percentage of S-phase cells induced by curcumin in HCT116 and SW480 cells after shNBR2 transfection and treated with 0 or 10 μM curcumin for 24 hours. Three independent experiments were performed, and the results are presented as the mean ± standard deviation. *P < 0.05, **P < .01. CRC indicates colorectal cancer.