Table 5. .
Metabolites | Sensitivity | Specificity | Accuracy | PPV | NPV | LHR +ve | LHR -ve |
Choline | 72 | 94.5 | 83 | 93.2 | 76.4 | 0.7701 | 0.7513 |
Choline/creatine (1.7) | 81.5 | 93.6 | 87.5 | 93 | 83 | 0.8801 | 0.86 |
Lactate | 68.4 | 33.6 | 51.3 | 51.6 | 50.7 | 2.0982 | 2.006 |
Choline + lactate | 93.8 | 90 | 93 | 92.3 | 85 | 1.0539 | 1.0311 |
Lipid | 74.4 | 62 | 68.7 | 67.2 | 70.8 | 1.2197 | 1.1839 |
N-acetyl aspartate | 44 | 30 | 37 | 39.4 | 34 | 1.5172 | 1.4333 |
Acetone | 10.5 | 42.7 | 26.3 | 16 | 31.5 | 0.2518 | 0.2225 |
Conventional MRI + MRS (All metabolites) | 97.4 | 93.3 | 91.7 | 90.2 | 90 | 1.0553 | 1.0332 |
LHR, likelihood ratio; MRS, MR spectroscopy; NPV, negative predictive value; PPV, positive predictive value.
Numbers are in percentage.