Table 5.

Summary of p20 functional lung dose-volume parameters in patients classified as RALI (n = 6) on CTCAE and those classified as no RALI on CTCAE (n = 38), at different radiotherapy dose thresholds (V5-50) and for the MLD

% p20 perfused volume	"RALI" (n = 6)	"No RALI" (n = 38)	% Diff between medians	Mann–Whitney p-value	ROC AUC (Az)
p20V5	55.7	50.9	4.8	0.472	0.60
p20V10	40.0	36.1	3.9	0.514	0.59
p20V13	30.7	26.0	4.8	0.514	0.59
p20V20	22.1	15.9	6.2	0.582	0.57
p20V30	18.0	9.8	8.3	0.472	0.60
p20V40	12.2	6.5	5.7	0.431	0.61
p20V50	6.8	3.5	3.2	0.514	0.59
p20MLD (cGy)	1356	1028	328	0.431	0.61

AUC, area under the curve; CTCAE, Common Toxic Criteria for Adverse Events; MLD, mean lung dose; RALI, radiation-associated lung injury; ROC, receiver operating characteristic.