Table 1.

Amyloid PET/CT – appropriate and inappropriate indications

APPROPRIATE	INAPPROPRIATE
Persistent or progressive unexplained MCI	Probable clinical AD and typical age of onset
Possible AD but unclear clinical presentation (atypical clinical course or an aetiologically mixed presentation)	To determine the severity of dementia
Early onset progressive dementia (usually defined as ≤65 years)	Asymptomatic patients with a family history of AD
	Asymptomatic patients shown to carry the ԑ4 allele of apolipoprotein E
	Cognitive complaint not confirmed on clinical examination
	In lieu of genotyping for suspected autosomal mutation carriers
	For non-medical reasons