Table 2.

Mechanism of action, patient preparation and image acquisition.^10,11

	18F-FDG	Amyloid Tracers (18F-florbetapir, flutemetamol, florbetaben)
Mechanism	Glucose analogue. Undergoes neuronal trapping enabling imaging and measurement of cerebral glucose metabolic rate10	Binds selectively to β-amyloid neuritic plaques. Biomarker of β-amyloid aggregate deposition11
Patient Preparation:	4–6 h fasting Avoid strenuous exercise Uptake period in standardized ambient conditions BM <10 in diabetic patients	No fasting No avoidance of exercise Standardized uptake conditions not required
Activity (mBq/mCi): Effective Dose (mSv):	250/7 5	185–370/5–10 5.8–7
Uptake Time (mins):	30	30–90
Acquisition Time (mins):	10	10–20