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Vitamin C induces apoptosis in human melanoma A375 cells. (A) Cells were treated with 0, 0.6, 1 and 1.4-mM vitamin C for 24 h and analyzed using Annexin V-FITC/PI by flow cytometry. (B) Histograms indicate apoptosis proportion from three separate experiments. **P<0.01 vs. Ctrl. FITC, fluorescein isothiocyanate; PI, propidium iodide; Ctrl, control.
