Table III.
Association between phosphor-protein kinase B expression and the clinicopathological variables of patients with esophageal squamous cell carcinoma.
| P-AKT expression | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Variables | (−) (n=29) | % | (+) (n=39) | % | (++) (n=16) | % | (+++) (n=1) | % | P-value |
| Sex | |||||||||
| Male | 13 | 44.8 | 28 | 71.8 | 11 | 68.8 | 1 | 100.0 | 0.041 |
| Female | 16 | 55.2 | 11 | 28.2 | 5 | 31.3 | 0 | 0.0 | |
| Age, years | |||||||||
| ≤66 | 14 | 48.3 | 21 | 53.8 | 9 | 56.3 | 1 | 100.0 | 0.456 |
| >66 | 15 | 51.7 | 18 | 46.2 | 7 | 43.8 | 0 | 0.0 | |
| Tumor location | |||||||||
| Cervical | 1 | 3.4 | 3 | 7.7 | 2 | 12.5 | 0 | 0.0 | 0.248 |
| Upper thoracic | 6 | 20.7 | 13 | 33.3 | 6 | 37.5 | 0 | 0.0 | |
| Middle thoracic | 15 | 51.7 | 18 | 46.2 | 5 | 31.3 | 0 | 0.0 | |
| Lower thoracic | 7 | 24.1 | 5 | 12.8 | 3 | 18.8 | 1 | 100.0 | |
| Tumor length, cm | |||||||||
| ≤5 | 10 | 34.5 | 19 | 48.7 | 7 | 43.8 | 1 | 100.0 | 0.281 |
| >5 | 19 | 65.5 | 20 | 51.3 | 9 | 56.3 | 0 | 0.0 | |
| Tumor volume, cm3 | |||||||||
| ≤25 | 8 | 27.6 | 12 | 30.8 | 6 | 37.5 | 0 | 0.0 | 0.611 |
| >25 | 21 | 72.4 | 27 | 69.2 | 10 | 62.5 | 1 | 100.0 | |
| T stage | |||||||||
| 1+2 | 14 | 48.3 | 22 | 56.4 | 3 | 18.7 | 0 | 0.0 | 0.117 |
| 3+4 | 15 | 51.7 | 17 | 43.6 | 13 | 81.3 | 1 | 100.0 | |
| N stage | |||||||||
| 0 | 12 | 41.4 | 19 | 48.7 | 4 | 25.0 | 0 | 0.0 | 0.309 |
| 1 | 17 | 58.6 | 20 | 51.3 | 12 | 75.0 | 1 | 100.0 | |
| Tumor-Node-Metastasis stage (17) | |||||||||
| I+II | 11 | 37.9 | 25 | 64.1 | 6 | 37.5 | 0 | 0 | 0.688 |
| III+IV | 18 | 62.1 | 14 | 35.9 | 10 | 62.5 | 1 | 100.0 | |
P-AKT, phosphor-protein kinase B.