. 2019 Aug 6;18(4):3501–3516. doi: 10.3892/ol.2019.10722

Table I.

Associations between the different MAGE family members and positive or negative lymph node status of patients with breast cancer.

MAGE family member	Affymetrix ID	Lymph node status	HR	95% CI	P-value
MAGEA5	214642_x_at	Positive	1.24^b	1.00–1.53^b	0.0447^b
		Negative	0.90	0.76–1.06	0.2129
MAGEA8	210274_at	Positive	1.22	0.99–1.52	0.0646
		Negative	0.85	0.71–1.03	0.0946
MAGEB4	207580_at	Positive	1.18	0.95–1.48	0.1385
		Negative	0.87	0.72–1.06	0.1809
MAGEB6	1552858_at	Positive	0.78	0.60–1.00	0.0515
		Negative	0.55^a	0.33–0.91^a	0.0188^a
MAGEB18	1552913_at	Positive	0.84	0.65–1.09	0.1869
		Negative	1.47	0.98–2.21	0.0601
MAGEC3	216592_at	Positive	1.20	0.98–1.48	0.0810
		Negative	0.85	0.71–1.01	0.0640
MAGED2	213627_at	Positive	0.79^a	0.65–0.96^a	0.0200^a
		Negative	0.82^a	0.68–0.99^a	0.0400^a
MAGED3	205028_at	Positive	0.81^a	0.67–0.99^a	0.0390^a
		Negative	1.10	0.93–1.30	0.2800
MAGED4	221261_x_at	Positive	1.24^b	1.02–1.51^b	0.0290^b
		Negative	1.27^b	1.07–1.51^b	0.0062^b
MAGEE1	1556047_s_at	Positive	0.81	0.62–1.04	0.1013
		Negative	0.79	0.54–1.17	0.2400
MAGEE2	1553254_at	Positive	1.23	0.95–1.58	0.1096
		Negative	0.57^a	0.33–0.98^a	0.0376^a
MAGEF1	218176_at	Positive	0.75^a	0.61–0.93^a	0.0094^a
		Negative	1.26^b	1.07–1.50^b	0.0063^b
MAGEH1	218573_at	Positive	1.30^b	1.04–1.62^b	0.0185^b
		Negative	0.91	0.75–1.11	0.3438
MAGEL2	219894_at	Positive	1.08	0.88–1.31	0.4600
		Negative	0.83^a	0.69–1.00^a	0.0464^a

P<0.05 was considered to indicate a statistically significant difference.

High mRNA expression levels associated with improved RFS

high mRNA expression levels associated with worse RFS. Total patients assigned a lymph node status, n=3,718; lymph node-positive patients, n=1,459; lymph node-negative patients, n=2,259, analyzed by ANOVA. CI, confidence interval; HR, hazard ratio; MAGE, melanoma-associated antigen; RFS, relapse-free survival.