. 2019 Aug 6;18(4):3501–3516. doi: 10.3892/ol.2019.10722

Table II.

Association between the MAGE family members and pathological tumor grade of patients with breast cancer.

MAGE family member	Affymetrix ID	Tumor grade	HR	95% CI	P-value
MAGEA5	214642_at	I	0.72	0.43–1.22	0.2269
		II	1.27	0.95–1.68	0.1038
		III	1.12	0.88–1.43	0.3578
MAGEA8	210274_at	I	0.63	0.33–1.22	0.1702
		II	0.74^a	0.57–0.96^a	0.0248^a
		III	0.78^a	0.61–0.99^a	0.0373^a
MAGEB4	207580_at	I	1.91^b	1.06–3.43^b	0.0288^b
		II	0.79	0.60–1.02	0.0732
		III	0.72^a	0.58–0.90^a	0.0041^a
MAGEB6	1552858_at	I	0.29^a	0.10–0.83^a	0.0136^a
		II	1.19	0.72–1.99	0.4982
		III	0.62^a	0.46–0.85^a	0.0029^a
MAGEB18	1552913_at	I	3.46^b	1.20–9.98^b	0.0142^b
		II	1.65	0.93–2.93	0.0840
		III	1.27	0.90–1.78	0.1706
MAGEC3	216592_at	I	1.51	0.80–2.85	0.2000
		II	0.74^a	0.57–0.96^a	0.0210^a
		III	0.89	0.71–1.11	0.2900
MAGED2	213627_at	I	1.47	0.87–2.48	0.1500
		II	0.86	0.67–1.10	0.2200
		III	1.39^b	1.11–1.73^b	0.0042^b
MAGED3	205028_at	I	1.64	0.95–2.83	0.0720
		II	0.79	0.62–1.01	0.0620
		III	1.35^b	1.07–1.69^b	0.0101^b
MAGED4	221261_x_at	I	0.54	0.26–1.10	0.0827
		II	1.52^b	1.18–1.95^b	0.0009^b
		III	1.20	0.97–1.50	0.0946
MAGEE1	1556047_s_at	I	0.35^a	0.12–1.02^a	0.0435^a
		II	0.61	0.35–1.05	0.0730
		III	1.53^b	1.12–2.08^b	0.0075^b
MAGEE2	1553254_at	I	0.56	0.19–1.67	0.2903
		II	1.22	0.73–2.04	0.4500
		III	1.18	0.87–1.61	0.2900
MAGEF1	218176_at	I	0.67	0.36–1.24	0.1993
		II	0.70^a	0.54–0.90^a	0.0057^a
		III	0.85	0.67–1.08	0.1788
MAGEH1	218573_at	I	0.52^a	0.30–0.88^a	0.0140^a
		II	0.63^a	0.47–0.85^a	0.0020^a
		III	1.18	0.94–1.49	0.1600
MAGEL2	219894_at	I	0.71	0.42–1.19	0.1907
		II	0.79	0.62–1.00	0.0513
		III	1.25^b	1.01–1.56^b	0.0420^b

P<0.05 was considered to indicate a statistically significant difference.

High mRNA expression levels associated with improved RFS

high mRNA expression levels associated with worse RFS. Total patients with a pathological tumor grade, n=2,545; patients with tumor grade I, n=378; patients with tumor grade II, n=1,077; patients with tumor grade III, n=1,090 patients. CI, confidence interval; HR, hazard ratio; MAGE, melanoma-associated antigen; RFS, relapse-free survival.